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1 Department of Physics, University of Agriculture Faisalabad, Faisalabad 38000, Pakistan;
2 Department of Physics, Government College University Faisalabad, Faisalabad 38000, Pakistan
* Correspondence: Muhammad Khawar Abbas, m_khawarabbas@yahoo.com; Yasir Javed, myasi60@hotmail.com
Journal of Optoelectronic and Biomedical Materials 2026, 18(1),32-48; https://doi.org/10.67229/JOBM16292
This study presented the synthesis of
pristine, chitosan, and polyethylene glycol
(PEG)–chitosan silver oxide nanoparticles (Ag3O4
NPs) using the hydrothermal technique and their potential for biological
applications. Nano-systems were characterized via X-ray diffraction
(XRD), UV-visible spectroscopy, Fourier transform infrared (FTIR)
spectroscopy, and scanning electron microscopy (SEM). The average
crystallite size of uncoated Ag3O4 NPs was 49 nm,
and it is significantly reduced in the case of chitosan and PEG–chitosan
conjugation, i.e., 25 nm and 22 nm, respectively. SEM micrographs
indicated the spherical morphology of all three nano-systems. The
chitosan and PEG–chitosan coating decreases the band gap of
Ag3O4 NPs. Antibacterial potential was evaluated
against E. coli and S. aureus. The antibacterial
potential was enhanced after chitosan and PEG conjugation of
Ag3O4 NPs. Chitosan-coated
Ag3O4 NPs were more suited to radical scavenging
for antioxidant properties, whereas in vitro alpha-amylase
inhibition was most significant for PEG–chitosan
Ag3O4 NPs.
