1 Department of Physics, Handique Girls' College, Guwahati-781001, Assam, India.
2 Advanced Level Institutional Biotech Hub, Handique Girls’ College, Guwahati-781001, Assam, India.
* Correspondence: uday.senapati@hgcollege.edu.in
Journal of Optoelectronic and Biomedical Materials 2026, 18(2),1-17; https://doi.org/10.67229/JOBM16196
This study presents a novel approach for synthesizing CdS nanoparticles by employing tea (Camellia sinensis L.) leaf catechins as a potent chelating agent. The production of spherical, cubic, and crystallite CdS nanoparticles was confirmed by XRD and HRTEM investigations. The existence of biomolecules that encapsulated and stabilized the CdS nanoparticles was verified by UPLC and FTIR analysis. These nanoparticles demonstrated antimicrobial activity against microorganisms isolated from spoiled Capsicum chinense Jacq. Additionally, the cytotoxic effect of CdS nanoparticles on HEK-293 normal kidney cells showed safe level of cytotoxicity. The theoretical investigation reveals a substantial interaction between CdS nanoparticles and the bio- constituents of tea. Therefore, due to their favorable biocompatibility, antimicrobial activity, and low cytotoxicity, the green synthesized CdS nanoparticles hold promise as a preservative to control microbial contamination of Capsicum chinense Jacq., thereby enhancing its shelf life.

