This Special Issue explores the convergence of bioactive materials with optoelectronic and photonic technologies for advanced medical applications. It focuses on the design, synthesis, and application of materials that actively interact with biological systems, specifically highlighting their integration into optical and electronic devices. We invite contributions on topics such as light-activated bioactive materials for photodynamic therapy, optoelectronic biosensors for real-time diagnostics, bioelectronic interfaces for neural stimulation, and luminescent nanoparticles for bioimaging. This issue aims to bridge materials science with biomedical engineering, showcasing how the unique properties of bioactive materials can be harnessed at the optoelectronic interface to create innovative solutions for therapy, diagnostics, and regenerative medicine. Original research and comprehensive reviews are welcome.

Aims and Scope of the Special Issue

The primary objective of this Special Issue is to highlight advances at the intersection of bioactive materials, optoelectronics, photonics, and biomedical applications. Particular emphasis will be placed on the development of materials that actively interact with biological systems and their integration into optical, electronic, and bioelectronic platforms for next-generation medical applications.

Submissions may include original research articles and comprehensive reviews addressing material design, synthesis, characterization, device integration, biological interaction, and medical applications. Particular emphasis will be placed on:

• Design and development of bioactive materials for medical applications

• Integration of bioactive materials with optoelectronic and photonic technologies

• Light-responsive and light-activated materials for therapeutic applications

• Optoelectronic and photonic platforms for biomedical sensing and diagnostics

• Bioelectronic interfaces for neural stimulation and related applications

• Luminescent and optically active nanomaterials for bioimaging

• Materials and devices for regenerative medicine and tissue engineering

• Structure–property relationships governing biological and optoelectronic performance

• Emerging materials strategies for multifunctional therapeutic and diagnostic systems

Suggested Topics (Non-exclusive)

Potential topics of interest include, but are not limited to:

• Bioactive nanomaterials for photodynamic therapy and light-activated treatments

• Photoresponsive and optically responsive biomaterials

• Optoelectronic biosensors for real-time and point-of-care diagnostics

• Photonic sensors and optical detection platforms for biomedical applications

• Bioelectronic materials and interfaces for neural stimulation and neuromodulation

• Conductive and electroactive bioactive materials

• Luminescent nanoparticles and nanocomposites for bioimaging

• Upconversion, fluorescent, and other optically active nanoparticles for medical applications

• Bioactive glasses, glass-ceramics, and related optical materials

• Multifunctional nanomaterials combining therapeutic and diagnostic functions

• Optoelectronic materials for drug delivery and controlled release

• Biomaterials for tissue engineering and regenerative medicine

• Flexible, wearable, and implantable optoelectronic biomedical devices

• Hybrid organic–inorganic materials for biomedical optoelectronics

• Surface-functionalized materials for biointerfaces and cellular interaction

• Computational design, characterization, and optimization of bioactive optoelectronic materials

• Emerging materials and device concepts for precision medicine and next-generation healthcare

Significance and Expected Impact

This Special Issue is expected to provide a focused platform for researchers working across materials science, optoelectronics, photonics, and biomedical engineering. By bringing together advances in bioactive materials and their integration with optical and electronic technologies, the issue aims to promote interdisciplinary approaches to emerging challenges in medical diagnostics, therapy, bioimaging, neural interfaces, and regenerative medicine.

The collected contributions are expected to demonstrate how the distinctive biological, optical, and electronic properties of advanced materials can be combined to develop multifunctional medical technologies. The Special Issue may also help identify emerging research directions and foster collaboration between materials scientists, engineers, physicists, chemists, and biomedical researchers.